Pipeline for Novel Product Isolation from Marine sponges (Phylum: Porifera) and Informatics Tools for the Process

Authors

  • Sheeja M S Assistant Professor, Dept. of Aquaculture, Govt. College of Arts & Science, Andrott Island, Lakshadweep-682551

Keywords:

Microbiome, Bioactive compounds, Sponge barcoding, Molecular taxonomy, Marine Natural Products

Abstract

Pharmaceutical industries are still searching for innovative drugs. Several diseases diagnosed hitherto have no effective medicine. Scientists are trying to discover novel drug entities with low toxicity to cure and prevent such diseases. A lead compound that has the properties of desired new drug is generally used as a model for chemical modification. Bacteria, fungi, plants and marine organisms consist of several natural products with low molecular mass and they exhibit unique structural diversity, and are used for identifying new lead structures. Marine sponges act as reservoirs of bioactive compounds with wide spectrum application in nutraceutical and pharmaceutical industries. Bioactive compounds such as alkaloids, terpenoids, sterols, peptides, polyketides etc. have been isolated from these organisms. There are different microbial communities (bacteria, fungi, actinomycetes) with novel bioactive compounds, which can be isolated from sponges and identification and isolation of novel compounds from sponges is a current area of research. The paper discusses the novel compound identification pipeline from marine sponges and outlines the pertinent informatics tools for the process.

Author Biography

  • Sheeja M S, Assistant Professor, Dept. of Aquaculture, Govt. College of Arts & Science, Andrott Island, Lakshadweep-682551

    Dr. Sheeja M.S. is working as an Assistant Professor at Government College of Arts and Science, Andrott, U.T of Lakshadweep. She did her Masters, M.Phil and PhD in Aquatic Biology and Fisheries, University of Kerala. She also had the opportunity to attend and complete a training program at Prince of Songkla University, Thailand. She has presented her research papers in many international conferences within India and presented a paper in an International conference at Malaysia. She has more than two years of experience as a lecturer in the field of Aquaculture, Fisheries and Marine Biology. Her major research areas of interests are taxonomy of opisthobranch molluscs and seaweeds, bioactive compound isolation from marine organisms.

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Published

2022-02-12

Issue

Vol. 9 No. 1 (2022): Marine Bioinformatics

Section

Articles

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